Nutrigenomics and Epigenetics
Know how your lifestyle choices interact with your genes

Epigenetics is one of the latest and most intensely studied fields of scientific research. It refers to situations where non-genetic factors cause your genes to behave (or "express themselves") differently. Some examples of factors that can epigenetically influence the expression of your genes include nutritional and lifestyle factors, exposure to toxins, quality of sleep and even emotions. These changes in genetic expression set in motion physiological events that will result in either better or worse functioning of your body; health or disease.

Nutrigenomics assesses how one’s genetic make-up determines what type of diet and other lifestyle factors are required to achieve and maintain good health. Nutrigenomic testing can detect genetic weaknesses that can make you vulnerable to diseases such as type 2 diabetes, obesity, heart disease, stroke and certain cancers. However, the types of genetic weakness studied in nutrigenomic (called single-nucleotide polymorphisms or SNPs) can be modified by specific lifestyle and dietary changes as well as individualised, targeted supplementation.

In order words specific diet and lifestyle changes can be prescribed to epigenetically modify the risks and benefits associated with your genetic makeup to minimise your genetic weakness while maximising your genetic strengths.


Nutrigenomic Testing

DNA Health: Optimise your health through gene-based personalised nutrition
DNA Diet: Genetic testing to assist with weight loss and weight gain

DNA Fit: Genetic testing to optimise your exercise and training
DNA Oestrogen: Genetic testing related to estrogen metabolism and breast cancer


DNA Health

The genes we carry significantly affect our health and susceptibility to various chronic diseases. Many diseases are preventable through the correct diet and lifestyle choices. DNA Health tests for variations in genes that play a crucial role in a number of metabolic processes which are key factors in the onset of chronic disease.

DNA Health is designed help you make the best diet and lifestyle choices based on your unique genetic make-up. It tests 20 genes involved in various key biological processes, including cholesterol metabolism, bone health, inflammation, antioxidant status, insulin sensitivity and vitamin B metabolism (including methylation). The results of this test can help formulate a plan to reduce your susceptibility to a wide variety of diseases from some cancers to depression.

R3500.00 (includes a follow-up consultation to explain the report)

The DNA Health test is available through Dr Cornelia Botha. If you would like to make an appointment to see Dr Botha, please contact her receptionist by visiting our contact page.

Back to the top of this page


DNA Diet:

Genetics can determine the way a person responds to diet and exercise, as well as an individual’s susceptibility to obesity when exposed to unfavourable environmental factors. In fact 40% to 80% of the variance in body weight is due to genetic factors. This helps to explain why not everyone becomes obese even though people may be exposed to similar environments.  Genes involved in the regulation of energy expenditure, insulin control, appetite and fat metabolism all play an important role in weight regulation.

DNA Diet is a genetic test that assesses 13 genes that impact metabolism and exercise. Your detailed report will include tailor made recommendations for nutrition and an exercise programme.

The DNA Diet test is available through Dr Cornelia Botha. The DNA Diet test is available through Dr Cornelia Botha. If you would like to make an appointment to see Dr Botha, please contact her receptionist by visiting our contact page.

R1500.00

If you would like to do additional testing to ensure that other diseases or hormone imbalances are not contributing to your weight gain or weight loss please contact our receptionist to make an appointment to see Dr Cornelia Botha by visiting our contact page.

Back to the top of this page


DNA Fit:

Where does your training performance potential lie? Are you a sprinter or should you be spending hours training for marathons? Personalise your training regime based on the knowledge of your genetic make-up.

DNA Fit is a genetic test that provides insight into your potential for sporting performance and trainability, optimal exercise selection, recovery strategies and injury management. The test is suitable for the elite performance athlete as well as the recreational athlete looking to maximise their training returns and reach peak levels of conditioning. DNA Fit tests for genes in three categories that relate to sporting performance: Power and Endurance, Recovery and Tendon Pathology.

R 2950.00

The DNA Fit test is available through Dr Cornelia Botha. If you would like to make an appointment to see Dr Botha, please contact her receptionist by visiting our contact page.

Back to the top of this page


Genetic testing related to estrogen metabolism and breast cancer

The Oestrogen Metabolism and Detoxification genetic test includes 10 single nucleotide polymorphisms (SNPs) involved in the production and metabolism of oestrogen, as well as the antioxidant, detoxification and methylation genes responsible for protecting against breast cancer. Research has shown that the risks associated with these SNPs are modifiable by individualised diet and lifestyle changes, as well as specific supplements.

R2500.00 (includes a 1 hour consultation to discuss the results of the testing)

Genetic testing for BRCA 1 and BRCA, which assesses the genetic susceptibility for breast and ovarian cancer within families, is separately available from Dr Botha.

The DNA Oestrogen test is available through Dr Cornelia Botha. To make an appointment with Dr Botha please visit our contact page.

Back to the top of this page


To make an appointment with Dr Cornelia Botha please contact her receptionist by visiting our contact page.